Vibrio natriegens as a high-performance platform for recombinant protein production

The marine bacterium Vibrio natriegens is currently recognised as the fastest-growing non-pathogenic bacterium. It features an exceptionally short doubling time of less than ten minutes, as well as remarkable metabolic versatility. These characteristics highlight its potential as a next-generation biotechnological production platform. Unlike established systems such as Escherichia coli, the potential of V. natriegens for producing recombinant proteins remains largely unexplored.

This project aims to establish the basis for the efficient use of V. natriegens in industrial biotechnology. Through targeted genomic engineering and optimised process strategies, existing limitations in recombinant protein production will be identified and overcome. Ultimately, the goal is to develop a robust portfolio of V. natriegens strains that can rapidly and reliably produce a variety of proteins.