Publications

Here all publications of our institute can be found, starting with the beginning of 2018.

2025

Fritzsche S., Popp M., Spälter L., Bonakdar N., Vogel N., Castiglione K.:
Recycling the recyclers: strategies for the immobilisation of a PET-degrading cutinase
In: Bioprocess and Biosystems Engineering (2025)
ISSN: 1615-7591
DOI: 10.1007/s00449-025-03131-7
Verhagen KJA., Pardijs IH., van Klaveren HM., Wahl SA.:
A Dive Into Yeast's Sugar Diet—Comparing the Metabolic Response of Glucose, Fructose, Sucrose, and Maltose Under Dynamic Feast/Famine Conditions
In: Biotechnology and Bioengineering (2025)
ISSN: 0006-3592
DOI: 10.1002/bit.28935

2024

Bergmann SM., Wang Y., Li Y., Wang Q., Klafack S., Jin Y., Hofmann AC., Kiełpińska J., Becker A., Zeng W.:
Occurrence of herpesvirus in fish
In: Journal of Veterinary Research 68 (2024), p. 73-78
ISSN: 2450-8608
DOI: 10.2478/jvetres-2024-0008
Brand L., Scherer M., tom Dieck T., Lotter S., Schäfer M., Burkovski A., Sticht H., Castiglione K., Schober R.:
Closed Loop Molecular Communication Testbed: Setup, Interference Analysis, and Experimental Results
ICC 2024 - IEEE International Conference on Communications (Denver, CO, 9th June 2024 - 13th June 2024)
In: ICC 2024 - IEEE International Conference on Communications 2024
DOI: 10.1109/ICC51166.2024.10622231
Essert A., Castiglione K.:
Dimer Stabilization by SpyTag/SpyCatcher Coupling of the Reductase Domains of a Chimeric P450 BM3 Monooxygenase from Bacillus spp. Improves its Stability, Activity, and Purification
In: ChemBioChem 25 (2024), Article No.: e202300650
ISSN: 1439-4227
DOI: 10.1002/cbic.202300650
Fritzsche S., Hübner H., Oldiges M., Castiglione K.:
Comparative evaluation of the extracellular production of a polyethylene terephthalate degrading cutinase by Corynebacterium glutamicum and leaky Escherichia coli in batch and fed-batch processes
In: Microbial Cell Factories 23 (2024), p. 274-
ISSN: 1475-2859
DOI: 10.1186/s12934-024-02547-2
Kober L., Strauch SM., Schwab S., Becker A., Erzinger GS., Castiglione K.:
Hop as a phytogenic alternative to antibiotic growth promoters in poultry production
In: Journal of the Science of Food and Agriculture (2024)
ISSN: 0022-5142
DOI: 10.1002/jsfa.13943
Steinmetz T., Thomas J., Reimann L., Himmelreich AK., Schulz S., Golombek F., Castiglione K., Jäck HM., Brodesser S., Warscheid B., Mielenz D.:
Identification of TFG- and Autophagy-Regulated Proteins and Glycerophospholipids in B Cells
In: Journal of Proteome Research 23 (2024), p. 1615-1633
ISSN: 1535-3893
DOI: 10.1021/acs.jproteome.3c00713
Walter T., Langbein M., Blenk P., Tesler A., Prado L., Bornstein D., Virtanen S., Castiglione K., Vogel N.:
Performance of environmentally friendly, liquid-infused coatings against biofouling: evaluation of macrofouling and microbially induced corrosion in freshwater environments
In: Journal of Materials Chemistry A (2024)
ISSN: 2050-7488
DOI: 10.1039/d4ta00741g
URL: https://pubs.rsc.org/en/content/articlelanding/2024/ta/d4ta00741g
tom Dieck T., Brand L., Lotter S., Castiglione K., Schober R., Schäfer M.:
Nanoscale Transmitters Employing Cooperative Transmembrane Transport Proteins for Molecular Communication
NANOCOM '24
In: NANOCOM '24: Proceedings of the 11th Annual ACM International Conference on Nanoscale Computing and Communication 2024
DOI: 10.1145/3686015.3689354

2023

Arevalo Villa C., Marienhagen J., Noack S., Wahl SA.:
Achieving net zero CO2 emission in the biobased production of reduced platform chemicals using defined co-feeding of methanol
In: Current Opinion in Biotechnology 82 (2023), Article No.: 102967
ISSN: 0958-1669
DOI: 10.1016/j.copbio.2023.102967
Arnold A., Castiglione K.:
Comparative Evaluation of the Asymmetric Synthesis of (S)-Norlaudanosoline in a Two-Step Biocatalytic Reaction with Whole Escherichia coli Cells in Batch and Continuous Flow Catalysis
In: Catalysts 13 (2023), Article No.: 1347
ISSN: 2073-4344
DOI: 10.3390/catal13101347
Brand L., Scherer M., Lotter S., tom Dieck T., Schäfer M., Burkovski A., Sticht H., Castiglione K., Schober R.:
Switchable Signaling Molecules for Media Modulation: Fundamentals, Applications, and Research Directions
In: IEEE Communications Magazine (2023), p. 1-7
ISSN: 0163-6804
DOI: 10.1109/MCOM.021.2300096
Eilts F., Jordan L., Harsy YM., Bergmann SM., Becker A., Wolff MW.:
Purification and concentration of infectious koi herpesvirus using steric exclusion chromatography
In: Journal of Fish Diseases (2023), p. 1-14
ISSN: 0140-7775
DOI: 10.1111/jfd.13800
Essert A., Castiglione K.:
Dimer Stabilization by SpyTag/SpyCatcher Coupling of the Reductase Domains of a Chimeric P450 BM3 Monooxygenase from Bacillus spp. Improves its Stability, Activity, and Purification
In: Chembiochem : a European journal of chemical biology (2023)
ISSN: 1439-7633
DOI: 10.1002/cbic.202300650
Essert A., Castiglione K.:
Enhancing the activity of a monomeric alcohol dehydrogenase for site-specific applications by site-directed mutagenesis
In: Protein Engineering Design & Selection 36 (2023)
ISSN: 1741-0126
DOI: 10.1093/protein/gzad006
Fritzsche S., Tischer F., Peukert W., Castiglione K.:
You get what you screen for: a benchmark analysis of leaf branch compost cutinase variants for polyethylene terephthalate (PET) degradation
In: Reaction Chemistry & Engineering (2023)
ISSN: 2058-9883
DOI: 10.1039/d3re00056g
Gallego-Murillo JS., Yağcı N., Pinho EM., Wahl SA., van den Akker E., von Lindern M.:
Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells
In: Scientific Reports 13 (2023), Article No.: 6960
ISSN: 2045-2322
DOI: 10.1038/s41598-023-32706-1
Lao-Martil D., Verhagen KJ., Valdeira Caetano AH., Pardijs IH., van Riel NA., Wahl SA.:
Using Kinetic Modelling to Infer Adaptations in Saccharomyces cerevisiae Carbohydrate Storage Metabolism to Dynamic Substrate Conditions
In: Metabolites 13 (2023), Article No.: 88
ISSN: 2218-1989
DOI: 10.3390/metabo13010088
Olavarria K., Becker MV., Sousa DZ., van Loosdrecht MC., Wahl SA.:
Design and thermodynamic analysis of a pathway enabling anaerobic production of poly-3-hydroxybutyrate in Escherichia coli
In: Synthetic and Systems Biotechnology 8 (2023), p. 629-639
ISSN: 2405-805X
DOI: 10.1016/j.synbio.2023.09.005
Paez-Watson T., Van Loosdrecht MCM., Wahl SA.:
Predicting the impact of temperature on metabolic fluxes using resource allocation modelling: Application to polyphosphate accumulating organisms
In: Water Research 228 (2023)
ISSN: 0043-1354
DOI: 10.1016/j.watres.2022.119365
Schorn F., Essert A., Zhong Y., Abdullayev S., Castiglione K., Haumann M., Joly N.:
Measurement of Minute Liquid Volumes of Chiral Molecules Using In-Fiber Polarimetry
In: Analytical Chemistry (2023)
ISSN: 0003-2700
DOI: 10.1021/acs.analchem.2c03347
Soares Rodrigues CI., den Ridder M., Pabst M., Gombert AK., Wahl SA.:
Comparative proteome analysis of different Saccharomyces cerevisiae strains during growth on sucrose and glucose
In: Scientific Reports 13 (2023), Article No.: 2126
ISSN: 2045-2322
DOI: 10.1038/s41598-023-29172-0

2022

Bergmann SM., Reichert M., Hwang J., Becker A., Lenk M., Kotterba G., Buchholz R., Jung S., Gebler A., Todte M., Kielpinska J., Lindenberger C.:
The application of exopolysaccharides (EPS) can prevent viral disease of fish.
In: Bulletin of the European Association of Fish Pathologists (2022), p. 1-12
ISSN: 0108-0288
DOI: 10.48045/001c.38087
Bergmann SM., Reichert M., Hwang J., Becker A., Lenk M., Kotterba G., Buchholz R., Jung S., Gebler A., Todte M., Kielpinska J., Lindenberger C.:
The application of exopolysaccharides (EPS) can prevent viral disease of fish
In: Bulletin of the European Association of Fish Pathologists 42 (2022), p. 15-27
ISSN: 0108-0288
DOI: 10.48045/001c.38087
Brand L., Garkisch M., Lotter S., Schäfer M., Burkovski A., Sticht H., Castiglione K., Schober R.:
Media Modulation based Molecular Communication
In: IEEE Transactions on Communications (2022), p. 1-1
ISSN: 0090-6778
DOI: 10.1109/TCOMM.2022.3205949
Brand L., Garkisch M., Lotter S., Schäfer M., Castiglione K., Schober R.:
Media Modulation in Molecular Communications
2022 IEEE International Conference on Communications, ICC 2022 (Seoul, 16th May 2022 - 20th May 2022)
In: IEEE International Conference on Communications 2022
DOI: 10.1109/ICC45855.2022.9838662
Gallego-Murillo JS., Iacono G., van der Wielen LA., van den Akker E., von Lindern M., Wahl SA.:
Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors
In: Biotechnology and Bioengineering (2022)
ISSN: 0006-3592
DOI: 10.1002/bit.28193
Gvaramia D., Kern J., Jakob Y., Tritschler H., Brenner RE., Breiter R., Kzhyshkowska J., Rotter N.:
THE RESPONSE OF PRIMARY HUMAN MACROPHAGES TO DECELLULARIZED NASAL SEPTAL CARTILAGE
In: TISSUE ENGINEERING PART A, NEW ROCHELLE: 2022
Huber L., Gvaramia D., Kern J., Jakob Y., Zoellner FG., Hirsch D., Breiter R., Brenner RE., Rotter N.:
In situ regeneration of nasal septal defects using acellular cartilage enhanced with platelet-derived growth factor
In: Journal of Tissue Engineering 13 (2022)
ISSN: 2041-7314
DOI: 10.1177/20417314221114423
Lao-Martil D., Verhagen KJA., Schmitz JP., Teusink B., Wahl SA., van Riel NA.:
Kinetic Modeling of Saccharomyces cerevisiae Central Carbon Metabolism: Achievements, Limitations, and Opportunities
In: Metabolites 12 (2022), Article No.: 74
ISSN: 2218-1989
DOI: 10.3390/metabo12010074
Piatka D., Frank A., Köhler I., Castiglione K., van Geldern R., Barth J.:
Balance of carbon species combined with stable isotope ratios show critical switch towards bicarbonate uptake during cyanobacteria blooms
In: Science of the Total Environment (2022), Article No.: 151067
ISSN: 0048-9697
DOI: 10.1016/j.scitotenv.2021.151067
Schäfer M., Brand L., Lotter S., Büyükoglu A., Enzenhofer F., Haselmayr W., Castiglione K., Appelhans D., Schober R.:
Controlled Signaling and Transmitter Replenishment for MC with Functionalized Nanoparticles
9th ACM International Conference on Nanoscale Computing and Communication (Barcelona, 4th October 2022 - 7th October 2022)
DOI: 10.1145/3558583.3558853
Tluczynski K., Breiter R.:
A compositional analysis of native and decellularized porcine nasal septum cartilage
In: Xenotransplantation (2022)
ISSN: 0908-665X
DOI: 10.1111/xen.12781
Urbanczyk S., Baris OR., Hofmann J., Taudte V., Guegen N., Golombek F., Castiglione K., Meng X., Bozec A., Thomas J., Weckwerth L., Mougiakakos D., Schulz S., Schuh W., Schlötzer-Schrehardt U., Steinmetz T., Brodesser S., Wiesner RJ., Mielenz D.:
Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling the flux of the TCA cycle
In: Cell Reports 39 (2022), p. 110912-
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2022.110912
Verhagen KJA., Eerden SA., Sikkema BJ., Wahl SA.:
Predicting Metabolic Adaptation Under Dynamic Substrate Conditions Using a Resource-Dependent Kinetic Model: A Case Study Using Saccharomyces cerevisiae
In: Frontiers in Molecular Biosciences 9 (2022), Article No.: 863470
ISSN: 2296-889X
DOI: 10.3389/fmolb.2022.863470

2021

Adamek M., Davies J., Beck A., Jordan L., Becker A., Mojzesz M., Rakus K., Rumiac T., Collet B., Brodgen G., Way K., Bergmann SM., Zou J., Steinhagen D.:
Antiviral Actions of 25-Hydroxycholesterol in Fish Vary With the Virus-Host Combination
In: Frontiers in Immunology 12 (2021), Article No.: 581786
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.581786
Dietschmann A., Schrüfer S., Westermann S., Henkel F., Castiglione K., Willebrand R., Ruland J., Lang R., Esser-Von-Bieren J., Radtke D., Krappmann S., Vöhringer D.:
PI3K signaling orchestrates eosinophil activation against Aspergillus fumigatus independently of canonical TLR/CLR signaling
In: MYCOSES, HOBOKEN: 2021
Fritzsche S., Blenk P., Christian J., Castiglione K., Becker A.:
Inhibitory properties of crude microalgal extracts on the in vitro replication of cyprinid herpesvirus 3
In: Scientific Reports 11 (2021), Article No.: 23134
ISSN: 2045-2322
DOI: 10.1038/s41598-021-02542-2
Golombek F., Haumann M., Knoll M., Fröba AP., Castiglione K.:
Three Steps, Two Enzymes, One Pot, but a Multitude of Nanocompartments: Combined Cycles of Kinetic Resolutions and Re-racemization with Incompatible Biocatalysts
In: ACS Omega 6 (2021), p. 29192-29200
ISSN: 2470-1343
DOI: 10.1021/acsomega.1c04694
Gvaramia D., Kern J., Jakob Y., Tritschler H., Brenner RE., Breiter R., Kzhyshkowska J., Rotter N.:
Modulation of the inflammatory response to decellularized collagen matrix for cartilage regeneration
In: Journal of Biomedical Materials Research Part A (2021)
ISSN: 1549-3296
DOI: 10.1002/jbm.a.37349
Heilmann M., Breiter R., Becker A.:
Towards rare earth element recovery from wastewaters: biosorption using phototrophic organisms
In: Applied Microbiology and Biotechnology (2021)
ISSN: 0175-7598
DOI: 10.1007/s00253-021-11386-9
Hobisch M., Spasic J., Malihan-Yap L., Barone GD., Castiglione K., Tamagnini P., Kara S., Kourist R.:
Internal Illumination to Overcome the Cell Density Limitation in the Scale-up of Whole-Cell Photobiocatalysis
In: Chemsuschem (2021)
ISSN: 1864-5631
DOI: 10.1002/cssc.202100832
Mertz M., Castiglione K.:
Increased protein encapsulation in polymersomes with hydrophobic membrane anchoring peptides in a scalable process
In: International Journal of Molecular Sciences 22 (2021), Article No.: 7134
ISSN: 1422-0067
DOI: 10.3390/ijms22137134
Mertz M., Golombek F., Boye S., Moreno S., Castiglione K.:
Fast and effective chromatographic separation of polymersomes from proteins by multimodal chromatography
In: Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 1162 (2021), Article No.: 122459
ISSN: 1570-0232
DOI: 10.1016/j.jchromb.2020.122459
Obst F., Mertz M., Mehner PJ., Beck A., Castiglione K., Richter A., Voit B., Appelhans D.:
Enzymatic Synthesis of Sialic Acids in Microfluidics to Overcome Cross-Inhibitions and Substrate Supply Limitations
In: ACS Applied Materials and Interfaces (2021)
ISSN: 1944-8244
DOI: 10.1021/acsami.1c12307

2020

Castiglione K., Schubeis T., Marchand L., Daday C., Kopec W., Movellan KT., Stanek J., Schwarzer TS., de Groot BL., Pintacuda G., Andreas LB.:
A beta-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL
In: Proceedings of the National Academy of Sciences of the United States of America 117 (2020), p. 21014-21021
ISSN: 0027-8424
DOI: 10.1073/pnas.2002598117
Golombek F., Castiglione K.:
Polymersomes as Nanoreactors Enabling the Application of Solvent-Sensitive Enzymes in Different Biphasic Reaction Setups
In: Biotechnology Journal (2020)
ISSN: 1860-6768
DOI: 10.1002/biot.201900561
Jurkowski W., Heilmann M., Becker A., Buchholz R., Brueck T.:
Terbium Excitation Spectroscopy as a Detection Method for Chromatographic Separation of Lanthanide-Binding Biomolecules
In: ACS Omega 5 (2020), p. 27050-27056
ISSN: 2470-1343
DOI: 10.1021/acsomega.0c02135
Schubeis T., Le Marchand T., Daday C., Kopec W., Movellan KT., Stanek J., Schwarzer TS., Castiglione K., de Groot BL., Pintacuda G., Andreas LB.:
A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL
In: Proceedings of the National Academy of Sciences of the United States of America 117 (2020), p. 21014-21021
ISSN: 0027-8424
DOI: 10.1073/pnas.2002598117
Schubeis T., Schwarzer TS., Le Marchand T., Stanek J., Movellan KT., Castiglione K., Pintacuda G., Andreas LB.:
Resonance assignment of the outer membrane protein AlkL in lipid bilayers by proton-detected solid-state NMR
In: Biomolecular NMR Assignments (2020)
ISSN: 1874-2718
DOI: 10.1007/s12104-020-09964-5
Söldner C., Socher E., Jamali V., Wicke W., Ahmadzadeh A., Breitinger HG., Burkovski A., Castiglione K., Schober R., Sticht H.:
A Survey of Biological Building Blocks for Synthetic Molecular Communication Systems
In: IEEE Communications Surveys & Tutorials 22 (2020), p. 2765-2800
ISSN: 1553-877X
DOI: 10.1109/COMST.2020.3008819
Ullrich J., Christian J., Bergmann SM., Oberle M., Becker A.:
Stability of viral haemorrhagic septicaemia virus, infectious hematopoietic necrosis virus and cyprinid herpesvirus 3 in various water samples
In: Journal of Fish Diseases (2020)
ISSN: 0140-7775
DOI: 10.1111/jfd.13321

2019

Ahmed IA., Hübner H., Mamoori YI., Buchholz R.:
The response of newly established cell lines of Spodoptera littoralis to group I and group II baculoviruses
In: Cytotechnology (2019)
ISSN: 0920-9069
DOI: 10.1007/s10616-019-00317-2
Amtmann A., Ahmed IA., Zahner-Rimmel P., Mletzko A., Jordan L., Oberle M., Wedekind H., Christian J., Bergmann SM., Becker A.:
Virucidal effects of various agents—including protease—against koi herpesvirus and viral haemorrhagic septicaemia virus
In: Journal of Fish Diseases (2019)
ISSN: 0140-7775
DOI: 10.1111/jfd.13106
Mähler C., Burger C., Kratzl F., Weuster-Botz D., Castiglione K.:
Asymmetric whole-cell bio-reductions of (R)-carvone using optimized ene reductases
In: Molecules 24 (2019), Article No.: 2550
ISSN: 1420-3049
DOI: 10.3390/molecules24142550
Mähler C., Kratzl F., Vogel M., Vinnenberg S., Weuster-Botz D., Castiglione K.:
Loop Swapping as a Potent Approach to Increase Ene Reductase Activity with Nicotinamide Adenine Dinucleotide (NADH)
In: dvanced Synthesis & Catalysis (2019)
ISSN: 0941-1216
DOI: 10.1002/adsc.201900073
Najbauer EE., Tekwani Movellan K., Schubeis T., Schwarzer T., Castiglione K., Giller K., Pintacuda G., Becker S., Andreas LB.:
Probing membrane protein insertion into lipid bilayers by solid-state NMR.
In: ChemPhysChem (2019)
ISSN: 1439-4235
DOI: 10.1002/cphc.201800793
Von Bomhard A., Elsaesser A., Riepl R., Pippich K., Faust J., Schwarz S., Körber L., Breiter R., Rotter N.:
Cartilage regeneration using decellularized cartilage matrix: Long-term comparison of subcutaneous and intranasal placement in a rabbit model
In: Journal of Cranio-Maxillofacial Surgery 47 (2019), p. 682-694
ISSN: 1010-5182
DOI: 10.1016/j.jcms.2019.01.010
Wang G., Castiglione K.:
Light-Driven Biocatalysis in Liposomes and Polymersomes: Where Are We Now?
In: Catalysts 9 (2019)
ISSN: 2073-4344
DOI: 10.3390/catal9010012

2018

Beck A., Jordan L., Herlitze S., Christian J., Brodgen G., Adamek M., Naim HY., Becker A.:
Quantification of sterols from carp cell lines via HPLC-MS
In: Separation Science Plus 1 (2018), p. 11-21
ISSN: 2573-1815
DOI: 10.1002/sscp.201700021
Castiglione K.:
Enzymkinetik
In: Horst Chmiel, Ralf Takors, Dirk Weuster-Botz (ed.): Bioprozesstechnik, Springer, 2018
DOI: 10.1007/978-3-662-54042-8_1
Castiglione K., Klermund L.:
Polymersomes as nanoreactors for preparative biocatalytic applications: current challenges and future perspectives
In: Bioprocess and Biosystems Engineering 9 (2018), p. 1233-1246
ISSN: 1615-7591
DOI: 10.1007/s00449-018-1953-9
Castiglione K., Weuster-Botz D.:
Enzymatische Prozesse
In: Horst Chmiel, Ralf Takors, Dirk Weuster-Botz (ed.): Bioprozesstechnik, Springer, 2018
DOI: 10.1007/978-3-662-54042-8_10
Dakhil H., Do H., Hübner H., Wierschem A.:
Measuring the adhesion limit of fibronectin for fibroblasts with a narrow-gap rotational rheometer
In: Bioprocess and Biosystems Engineering 41 (2018), p. 353-358
ISSN: 1615-7591
DOI: 10.1007/s00449-017-1868-x
URL: https://link.springer.com/article/10.1007/s00449-017-1868-x?wt_mc=Internal.Event.1.SEM.ArticleAuthorAssignedToIssue
Goldberg-Bockhorn E., Schwarz S., Subedi R., Elsässer A., Riepl R., Walther P., Körber L., Breiter R., Stock K., Rotter N.:
Laser surface modification of decellularized extracellular cartilage matrix for cartilage tissue engineering
In: Lasers in Medical Science 33 (2018), p. 375-384
ISSN: 0268-8921
DOI: 10.1007/s10103-017-2402-8
Schwarzer TS., Klermund L., Wang G., Castiglione K.:
Membrane functionalization of polymersomes: alleviating mass transport limitations by integrating multiple selective membrane transporters for the diffusion of chemically diverse molecules.
In: Nanotechnology 29 (2018), p. 44LT01
ISSN: 0957-4484
DOI: 10.1088/1361-6528/aadb7e